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唐·杨(Don Young)是一位生物统计学家,在第4阶段前列腺癌中幸存

2025/05/23 17:42

唐·杨(Donn Young)是俄亥俄州立大学综合癌症中心生物统计学部门的前任主任,他花了32年的时间设计,进行和分析癌症研究。

唐·杨(Don Young)是一位生物统计学家,在第4阶段前列腺癌中幸存

Like former President Joe Biden, I was recently diagnosed with stage 4 prostate cancer.

像前总统乔·拜登(Joe Biden)一样,我最近被诊断出患有第4期前列腺癌。

It was a sunny Thursday morning in March when I received a phone call from Dr. William Lee, a radiologist at Ohio State University, to tell me that one of the bone metastases had increased in size.

这是3月的星期四早晨,当我接到俄亥俄州立大学放射科医生William Lee博士的电话,告诉我其中一种骨转移的大小增加了。

Since my cancer had spread to many bones, the cancer was deemed incurable and my prognosis was not good even though I had no symptoms.

由于我的癌症已经扩散到许多骨骼上,因此癌症被认为是无法治愈的,即使我没有症状,我的预后也不好。

In fact, the median survival for men like me with advanced prostate cancer at the time of diagnosis was 30 months —so I had less than a 50-50 chance of living three years.

实际上,诊断时患有晚期前列腺癌的男性的中位生存期为30个月 - 因此,我的生活机会不到50-50的机会。

When I was diagnosed, I was a biostatistician designing and analyzing clinical trials at Ohio State University Comprehensive Cancer Center.

当我被诊断出时,我是一名生物统计学家,正在俄亥俄州立大学综合癌症中心设计和分析临床试验。

I had co-authored journal articles on prostate cancer so I knew that with bone metastases my chances were not good and that there was no treatment that offered a cure.

我合着了有关前列腺癌的期刊文章,所以我知道,随着骨转移的机会,我的机会不好,没有治疗方法可以治愈。

I had just completed a grant funded by the National Cancer Institute to increase the enrollment of minorities on clinical trials. Dr. William Hicks, a local oncologist, and I encouraged people with a cancer diagnosis that if they were eligible, a clinical trial was their best bet.

我刚刚完成了由国家癌症研究所资助的赠款,以增加少数民族在临床试验中的入学人数。当地肿瘤学家威廉·希克斯(William Hicks)博士,我鼓励患有癌症诊断的人,如果他们符合条件,临床试验是最好的选择。

It was now my turn to step up and volunteer for an experimental study.

现在轮到我加强并自愿进行实验研究了。

A flip of a coin

硬币的翻转

Dr. Steven Clinton, a friend, colleague, and urologic oncologist at OSU, enrolled me on a randomized trial, where my treatment was selected by flipping a coin. I began treatment with hormone ablation therapy to decrease testosterone that was fueling the growth and spread of my cancer.

OSU的朋友,同事和泌尿科肿瘤学家Steven Clinton博士让我参加了一项随机试验,在那里我通过翻转硬币选择了我的治疗方法。我开始接受激素消融疗法的治疗,以减少睾丸激素,从而加剧了癌症的生长和传播。

That was in 2007 - 18 years ago. My cancer was very sensitive to hormonal control. And while I have had no evidence of residual cancer for many years, I continue the treatment started years ago.

那是在2007年 - 18年前。我的癌症对荷尔蒙控制非常敏感。尽管我多年来一直没有残留癌症的证据,但我继续治疗几年前。

The clinical trial ended a decade ago with my treatment being found to be the better of the two treatments being tested. I was very lucky to be one of the few long-term survivors of this disease. Unfortunately, there is still no way to determine at the time of diagnosis who will do well and who will not.

临床试验在十年前结束时,发现我的治疗是正在测试的两种治疗方法中的更好。我很幸运能成为这种疾病的少数长期幸存者之一。不幸的是,在诊断时仍无法确定谁会做得很好,谁将做得不好。

What's really important

真正重要的是什么

My late wife, Phyllis Kaldor, who was a director of nursing at OSU’s James Cancer Hospital, had planned to care for me during my final days. She, however, developed metastatic cancer of the appendix. Thus, it fell to me with the help of family and friends to care for her until she passed away in 2013.

我已故的妻子菲利斯·卡尔多(Phyllis Kaldor)是OSU詹姆斯癌症医院(OSU James Cancer Hospital)护理董事的董事,他计划在我的最后几天照顾我。但是,她患上了附录的转移性癌。因此,在她的家人和朋友的帮助下,照顾她,直到她于2013年去世。

A cancer diagnosis focuses one’s attention on what’s really important and it’s not money, power, and prestige.

癌症诊断将注意力集中在真正重要的事情上,而不是金钱,权力和声望。

It comes down to love and connections with family and friends. Despite the loss and grief that we all come to experience, I have learned that it’s really the small things that matter: a kiss from someone who loves you more than anyone else, a smile from your children, and a giggle from your grandchild.

这取决于与家人和朋友的爱与联系。尽管我们都经历了损失和悲伤,但我了解到,这确实是重要的事情:一个比其他人更爱您的人,孩子的微笑,以及您孙子的咯咯笑。

Bringing joy to your life might include chatting with neighbors, enjoying the company of new and old friends, creating something with your hands, and learning to play a ukulele (or lesser instrument).

为生活带来欢乐,可能包括与邻居聊天,享受新老朋友的陪伴,用手创造一些东西,并学习演奏夏威夷四弦琴(或较少的乐器)。

Like for all of us following a cancer diagnosis, Biden’s journey will be uniquely his own, but given the strength, resilience, and grace he has shown in the past, I am confident that he and his family will continue to have hopes for the future and love for one another.

就像我们所有人经过癌症诊断后一样,拜登的旅程将是他自己的独特之处,但是鉴于他过去所表现出的力量,韧性和优雅,我相信他和他的家人将继续对未来并彼此相爱。

Our best wishes go with him.

我们最良好的祝愿与他同在。

Donn Young is the former director of the Ohio State University Comprehensive Cancer Center Biostatistics Unit where he spent 32 years designing, conducting, and analyzing cancer research studies. He now spends his time seeing his daughters, helping care for his grandsons, 2-year-old James Patrick and 9-month-old Lincoln, travel with his sweetie, making pottery, kayaking, playing his ukulele (John Prine’s his favorite), and birding.

唐·杨(Donn Young)是俄亥俄州立大学综合癌症中心生物统计学部门的前任主任,他花了32年的时间设计,进行和分析癌症研究。现在,他花时间看女儿,帮助照顾孙子,2岁的詹姆斯·帕特里克(James Patrick)和9个月大的林肯(Lincoln),和他的甜心一起旅行,做陶器,划独木舟,扮演夏威夷夏威夷夏威夷四弦琴(约翰·普林(John Prine)的最爱)和观鸟。

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