Washington — The Senate is expected to take a key procedural vote Monday evening on a crypto regulation bill

The first-of-its-kind legislation, known as the GENIUS Act, would create a regulatory framework for stablecoins — a type of cryptocurrency tied to the value of an asset like the U.S. dollar.

The Senate is set to take a key procedural vote Monday evening on a bipartisan crypto regulation bill after Democratic opposition tanked an initial attempt to advance the measure earlier this month amid concern over ties between the digital asset industry and the Trump family.

The first-of-its-kind legislation, known as the GENIUS Act, would create a regulatory framework for stablecoins — a type of cryptocurrency tied to the value of an asset like the U.S. dollar. After the measure advanced out of the Senate Banking Committee with bipartisan support in March, Senate GOP leadership first brought the bill to the floor earlier this month. But the measure had lost Democratic support in the intervening weeks amid concerns about President Trump and his family's business ventures involving cryptocurrency.

Majority Leader John Thune said the upper chamber would try again to advance the legislation on Monday, criticizing Democrats for blocking the measure from moving forward earlier this month.

"This bill reflects the bipartisan consensus on this issue, and it's had an open and bipartisan process since the very beginning," Thune said. "Senate Democrats, however, inexplicably chose to block this legislation from moving forward earlier this month."

The South Dakota Republican added: "I'm hoping that the second time will be the charm. We can get this bill passed with bipartisan support and President Biden's signature."

Since the failed vote earlier this month, negotiators returned to the table. And ahead of the procedural vote Monday, the measure saw backing from at least one Democrat as Sen. Mark Warner of Virginia advocated for the bill, calling it a "meaningful step forward."

"This bill is not perfect, but it is a meaningful step forward in setting up the U.S., the global leader in financial technology, for long-term success," Warner said in a statement. "The stablecoin market has reached nearly $250 billion and the U.S. can't afford to keep standing on the sidelines. We need clear rules of the road to protect consumers, defend national security, and support responsible innovation."

Still, Warner pointed to concerns he said are shared among many senators about the Trump family's "use of crypto technologies to evade oversight, hide shady financial dealings, and personally profit at the expense of everyday Americans."

Earlier this month, it was announced that an Abu Dhabi-backed firm will invest billions of dollars in a Trump family-linked crypto firm, World Liberty Financial.

Senators "have a duty to shine a light on these abuses," but Warner argued "we cannot allow that corruption to blind us to the broader reality: blockchain technology is here to stay."

Whether the measure can advance in the upper chamber this time around remains to be seen. The bill fell short of the 60 votes necessary to move forward earlier this month, with all Senate Democrats and two Republicans — Sens. Rand Paul of Kentucky and Josh Hawley of Missouri — opposing the bill. Paul had reservations about overregulation, while Hawley voted against the bill in part because it doesn't prohibit big tech companies from creating their own stablecoins.

Sen. Bill Hagerty of Tennessee, who sponsored the legislation, defended the measure Monday on CNBC's "Squawk Box."

Hagerty outlined that a lack of regulatory framework, which the bill would provide, makes for uncertainty — and results in innovative technology moving offshore.

"This will fix it," Hagerty urged, arguing that the bill has strong bipartisan support.

"We have broad policy agreement, Democrats and Republicans," Hagerty said. "The question is can we get past the partisan politics and allow us to actually have a victory."

Kaia Hubbard is a politics reporter for CBS News Digital, based in Washington, D.C.