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我們的新聞是如何製作的

Placebo used in a new study to treat moderate-to-severe lower back pain had no effect on pain or physical function over a three-month period, according to new research published in JAMA Network Open.

根據JAMA Network Open發表的新研究，在一項新研究中使用的安慰劑用於治療中背部疼痛，對三個月內的疼痛或身體功能沒有影響。

The study, which included 120 adults with lower back pain, also found that the use of the placebo did not influence participants' beliefs about the treatment or satisfaction with care.

這項研究包括120名下背部疼痛的成年人，還發現安慰劑的使用不會影響參與者對治療或對護理滿意的信念。

The researchers, from the University of Washington in Seattle, said their findings are important because they add to a growing body of evidence that placebos alone may not provide lasting benefit for chronic pain.

來自西雅圖華盛頓大學的研究人員說，他們的發現很重要，因為他們增加了越來越多的證據表明，僅安慰劑可能不會為慢性疼痛帶來持久的好處。

"Our findings suggest that, at least in the short term, the use of a placebo in the setting of routine care for back pain does not appear to exert an effect on pain, physical function, or patient-reported outcomes," they wrote.

他們寫道：“我們的發現表明，至少在短期內，在常規護理背痛的情況下使用安慰劑似乎不會對疼痛，身體功能或患者報告的結果產生影響。”

The researchers said they were surprised by their findings, given that previous studies have shown that placebos can have a significant impact on pain perception in the lab setting.

研究人員說，鑑於先前的研究表明，安慰劑對實驗室環境中的疼痛感可能產生重大影響，因此他們對他們的發現感到驚訝。

However, they said the new study was conducted in a real-world setting, which may explain why the effects of the placebo were smaller and did not last as long.

但是，他們說，這項新研究是在現實世界中進行的，這可以解釋為什麼安慰劑的影響較小，並且持續不長。

The researchers also noted that the study was relatively small and more research is needed to fully understand the role of placebos in pain management.

研究人員還指出，這項研究相對較小，需要更多的研究來充分了解安慰劑在疼痛管理中的作用。

"These findings may not be generalizable to other patient populations, such as those with cancer pain or headache, or to other chronic pain conditions," they said.

他們說：“這些發現可能無法推廣到其他患者人群，例如患有癌症疼痛或頭痛的患者或其他慢性疼痛狀況。”

"The short-term nature of this study also limits the detection of potential long-term effects of placebo on pain and function."

“這項研究的短期性質還限制了安慰劑對疼痛和功能的潛在長期影響的檢測。”

Despite the null findings, the researchers said their study highlights the importance of considering the psychological and social factors that may influence pain perception and response to treatment.

儘管發現無效，但研究人員說，他們的研究強調了考慮可能影響疼痛感知和對治療反應的心理和社會因素的重要性。

They said it is possible that the placebo group in their study experienced less improvement in pain and function because they had higher expectations for the treatment or were less satisfied with the care they received.

他們說，他們的研究中的安慰劑組可能在疼痛和功能方面的改善較小，因為他們對治療的期望更高，或者對接受的護理不太滿意。

"It is also possible that the members of the placebo group had a less positive anticipation of the treatment effect or were less engaged in the treatment process," they said.

他們說：“安慰劑組的成員對治療效果的預期較少，或者參與治療過程的積極期望較低。”

The researchers said they plan to conduct further studies to examine the role of these factors in determining the effects of placebos for chronic pain.

研究人員說，他們計劃進行進一步的研究，以研究這些因素在確定安慰劑對慢性疼痛影響的作用中的作用。

The new study is the latest to examine the role of placebos in treating chronic pain. A 2019 study published in the journal Science found that placebos could reduce pain in patients with osteoarthritis of the knee.

這項新研究是檢查安慰劑在治療慢性疼痛中的作用的最新研究。 2019年發表在《科學》雜誌上的一項研究發現，安慰劑可以減輕膝蓋骨關節炎患者的疼痛。

However, another study published in 2020 in the journal Annals of Internal Medicine found no evidence that placebos were effective for treating chronic low back pain.

但是，另一項在2020年發表在《內科雜誌》雜誌上的研究沒有證據表明安慰劑可有效治療慢性腰痛。

The researchers said their findings have implications for the way chronic pain is treated.

研究人員說，他們的發現對慢性疼痛的治療方式具有影響。

"Despite the widespread interest in exploring the role of placebo effects in pain modulation, there is limited evidence to support the use of placebos in the setting of routine care for chronic pain," they said.

他們說：“儘管對探索安慰劑作用在疼痛調節中的作用的興趣普遍存在，但仍有有限的證據支持安慰劑在常規護理慢性疼痛的情況下使用。”

"Our findings add to a growing body of literature suggesting that, at least in the short term, placebos alone may not provide benefit for patients with chronic pain."

“我們的發現增加了越來越多的文獻，這表明至少在短期內，僅安慰劑可能不會為患有慢性疼痛的患者帶來好處。”