Semler Scientific Buys the Dip, Acquiring 455 Bitcoin (BTC) for $50M

Semler Scientific, a Nasdaq-listed medical technology and software company based in California, has acquired a significant amount of Bitcoin (BTC).

Nasdaq-listed medical technology and software company Semler Scientific has bought a significant amount of Bitcoin (BTC).

Semler bought an additional 455 BTC — its third-largest purchase since adopting a Bitcoin standard roughly one year ago.

Semler Buys Millions More In Bitcoin

According to the May 23 8-K filing, Semler bought the Bitcoin for $50 million. The company bought 455 BTC for an average purchase price of $109,801 per coin. Semler bought the Bitcoin using part of the proceeds from its $500 million at-the-market offering program.

The company issued 3,003,488 shares under its April 15 $500 million ATM program, generating $114.8 million.

Semler now has 4,264 BTC on its books, valued at approximately $474.4 million. It bought the BTC for an aggregate of $390 million at an average cost basis of $91,471.

The medical device company has been aggressively purchasing Bitcoin since last year, mirroring the playbook pioneered by Strategy (formerly MicroStrategy) and its Chairman and renowned Bitcoin supporter, Michael Saylor.

Semler’s BTC Yield has jumped to 25.8% in 2025. BTC yield, a performance indicator popularized by Saylor and Strategy, refers to the company’s Bitcoin holdings divided by its assumed diluted shares outstanding.

At 4,264 BTC, the company’s Bitcoin treasury ranks 13th in size among publicly traded companies, according to BitcoinTreasuries data.

Corporate Treasury Boom

Software intelligence company Strategy began buying BTC in 2020 at the behest of former CEO Michael Saylor. Since then, the company has amassed a 576,230 BTC stash, currently valued at approximately $62 million.

There are now more than 70 firms that have incorporated a Bitcoin treasury, with Cantor Fitzgerald, SoftBank, Bitfinex, and Tether recently announcing the forthcoming launch of a $3.6 billion Bitcoin venture, Twenty One.

Other companies, including Japanese investment firm Metaplanet, have also followed in Strategy’s footsteps and continue stacking the world’s oldest and largest cryptocurrency.